Norman Bethune International Institute of Canada

Publications

Peer-reviewed publications reflecting NBIIC-HI’s research focus in mechanism-driven translational medicine, immunoregulation, microenvironment modulation, and targeted therapeutic innovation.

2026

NGR-modified cancer-associated fibroblast-derived exosomes deliver resveratrol to inhibit CXCR2/NF-κB signaling and reverse immune suppression in liver cancer.

International Immunopharmacology.

Research area: Extracellular vesicles; targeted delivery; immunoregulation; liver cancer.

PAARH suppresses Kupffer cell phagocytosis to promote tumor liver metastasis by upregulating CD47.

Cancer Cell International.

Research area: Tumor microenvironment; Kupffer cells; CD47; liver metastasis.

Integrative Genomic Analysis Reveals Insulin Resistance as a Key Mediator in the Causal Link Between Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Hypertension.

JMA Journal.

Research area: MASH; insulin resistance; hypertension; integrative genomics; causal mediation.

Selected Earlier Publications

Mechanism of congenital lymphocytes and intestinal immunity regulated by gut microbial metabolites via metabolite-sensing receptor Ffar2.

Cancer Insight.

Research area: Microbiome–immune regulation; intestinal inflammation; metabolite-sensing receptors; Ffar2 signaling; translational immunology.